World Diabetes Day is the largest diabetes awareness campaign in the world to call attention to the prevention and management of diabetes. The theme of World Diabetes Day 2023 is “Know the Risk, Know the Response” and focuses on the prevention and delay of type 2 diabetes.
One in 10 adults worldwide has diabetes, and more than 90% have type 2 diabetes. Nearly half have not yet been diagnosed. In many cases, diabetes and its complications can be delayed or prevented by developing and maintaining healthy habits. It is hoped that more people can understand the harm of diabetes to different people through “World Diabetes Day”, choose more scientific and effective prevention and control measures, improve their own and their families’ awareness of prevention, control and delay the occurrence of diabetes. Early diagnosis and prompt treatment are very important.
Diabetes is a “gentle and sweet” killer. The initial rise in blood sugar often has no obvious symptoms, so many people do not pay enough attention to diabetes and do not pay attention to the harm caused by diabetes. However, with the prolonged course of the disease, it will cause a variety of harm to the body, and even endanger life. Globally, diabetes is on the rise and has become a serious public health challenge.
Who is prone to diabetes?
- Obesity: more than 20% of the ideal body weight;
- Relatives with diabetes;
- Hypertension and hyperlipidemia;
- Increased blood sugar, positive urine sugar, etc.;
- Have delivered a baby weighing more than 4kg;
- Middle-aged and elderly people over 40 years old.
Dangers of diabetes
- Diabetic myocardial infarction
- Diabetic cerebral infarction
- Subacute complications
Who needs blood sugar screening?
- Adults over 40 years old are recommended to check their blood sugar at least once a year to determine the specific situation.
- Obese people with BMI≥23, or waist circumference exceeding 90cm for men and 85cm for women.
- People whose parents or siblings have diabetes.
- Patients with hypertension, dyslipidemia, cardiovascular diseases, polycystic ovary syndrome and other diseases, as well as psychotropic drug use.
How to prevent diabetic cardiovascular disease?
Comprehensive control of cardiovascular risk factors
Sugar friends should completely change the traditional treatment concept of simple blood sugar control as the center, to start from a comprehensive approach, actively and strictly control hypertension, correct dyslipidemia, but also to control weight, quit smoking.
Control sugar smoothly
Good blood sugar control can reduce the risk of heart disease and death, and large fluctuations in blood sugar are even more harmful than sustained high blood sugar. In the process of using hypoglycemic drugs, it is necessary to follow the doctor’s advice, and do not arbitrarily increase the dose or stop the drug without authorization, so as to maintain stable blood sugar and reduce blood sugar fluctuations.
A severe bout of hypoglycemia may cancel out the benefits of long-term blood sugar control, leading to constriction of blood vessels, hypoxia of the heart, arrhythmia, acute myocardial infarction, and even death. For elderly patients and diabetic patients with cardiovascular disease, the target of blood glucose control can be appropriately relaxed.
Insulin-like Growth Factor Binding Protein，IGFBP，is a group of proteins that bind to Insulin-like Growth factors (IGF), including IGFBP-1 to IGFBP-7.
IGFBP has many physiological functions in human body, including regulating the activity of IGF and participating in cell proliferation, differentiation and apoptosis. In addition, IGFBP is also associated with a variety of diseases, such as diabetes, cancer, cardiovascular disease and so on.
In the diagnosis and treatment of diabetes, IGFBP also has certain application value. Studies have shown that levels of IGFBP-1 and IGFBP-3 are closely related to the onset and development of diabetes. Therefore, the diagnosis and treatment of diabetes can be aided by the detection of IGFBP-1 and IGFBP-3 levels in the blood.